Perfluorochemical fluids (PFC) are derived from common organic compounds by replacing the carbon-bound hydrogen atoms with fluorine atoms. They are clear, colorless, and odorless. Oxygen, carbon dioxide and other gases are highly soluble in these fluids. PFC liquids have a low surface tension. Additionally, PFC liquids have a low surface tension and are inert and non-biotransformable.  They are stable and can be stored at room temperature indefinitely and can be autoclaved. There are hundreds of different PFC fluids with unique biomedical properties.
PFC fluids are minimally absorbed, removed by vaporization through the lungs and do not cause long term adverse histologic, biochemical or toxic effects.  This is due to the inert and non-biotransformable physical properties of PFC fluid.
Physical Properties Saline FC-75
perfluoroalkylfuran
Perflubron
perfluorooctylbromide
APF=140
perfluorodecalin
O2 Solubility @ 25°C
(ml gas/100 ml liquid)
3 52 53 49
CO2 Solubility @ 37°C
(ml gas/100 ml liquid)
57 160 210 140
Surface Tension
(dynes/cm @ 25°C)
72 15 18 15
Vapor Pressure
(torr @ 37°C)
47 63 11 14
Density @ 25°C
(gm/ml)
1.00 1.78 1.93 1.95
Dynamic Viscosity
(centipose @ 25°C)
1.00 1.46 2.12 5.65
Kinematic Viscosity
(centistokes @ 25°C)
1.00 0.82 1.10 2.90





Physical Properties of Saline and 3 Perflurochemical Fluids
Neonatal Liquid Ventilation